Actively Recruiting

Phase Not Applicable
Age: 5Years +
All Genders
ID07196436

Energy Recovery Ventilation and Air Cleaner Interventions to Improve Indoor Air Quality, Mold Control, and Asthma-Related Health Outcomes Among Inner-City Children and Adults in Low-Income Households

Led by The University of Texas at Arlington · Updated on 2025-10-29

80

Participants Needed

2

Research Sites

4 weeks

Total Duration

On this page

Sponsors

T

The University of Texas at Arlington

Lead Sponsor

R

Rebuilding Together North Texas

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research aims to evaluate the long-term effectiveness of two devices, energy recovery ventilators (ERVs) and portable air cleaners (PACs), in lowering indoor air pollutants and mold while improving asthma-related health outcomes among children and adults with asthma living in low-income households in the Dallas-Fort Worth metropolitan area. The study uses a double-blind, placebo-controlled randomized controlled design to compare these interventions over a year, focusing on asthma control, quality of life, stress, and sleep quality. Participants will be randomly assigned to one of four groups: an active ERV, a placebo ERV (operating only in recirculation mode), an active PAC, or a placebo PAC (lacking HEPA and carbon filters). The ERVs use filters to clean incoming outdoor air, while PACs filter indoor air pollutants. The study includes baseline housing assessments and indoor air measurements to understand environmental factors affecting asthma and the impact of these devices. Participants will undergo comprehensive health assessments including lung function tests and monthly asthma control surveys for up to two years, covering one year before and one year after the intervention begins. Additional assessments include quality of life, stress, and sleep evaluations using validated questionnaires during home visits. Environmental exposures, housing conditions, and asthma outcomes will be monitored to measure the effects of the interventions, with safety and health tracked throughout the study period.

CONDITIONS

Brief Title

Asthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study

Who Can Participate

Age: 5Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Individuals with physician-diagnosed asthma, including both adults and children aged 5-17
  • Homeowners living in the Dallas-Fort Worth metropolitan area, TX
Not Eligible

You will not qualify if you...

  • Participants living in homes with any smokers

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - 1 year

Participants are randomized to receive one of four home device interventions: an active energy recovery ventilator, a sham energy recovery ventilator, an active portable air cleaner, or a sham portable air cleaner, installed in their homes.

Monthly home visits for asthma control assessments and periodic home visits for quality of life, stress, and sleep evaluations at baseline, 6, 18, and 24 months

Long-term Monitoring

Duration - 1 year

Participants are observed for ongoing asthma control, indoor air quality, and health outcomes following the intervention period.

Monthly asthma control assessments continuing through the full 24 months with additional home visits at 18 and 24 months for comprehensive evaluations

Trial Site Locations

Total: 2 locations

1

University of Texas at Arlington

Arlington, Texas, United States, 76010

Actively Recruiting

2

Rebuilding Together North Texas

Plano, Texas, United States, 75025

Actively Recruiting

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Research Team

I

Insung Kang, Ph.D.

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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Published Research Related To This Trial

Study protocol for a 1-year, randomized, single-blind, parallel group trial of stand-alone indoor air filtration in the homes of US military Veterans with moderate to severe COPD in metropolitan Chicago.

Brent Stephens, Insung Kang, Kaveeta Jagota...

https://pubmed.ncbi.nlm.nih.gov/40468409

Impacts of residential indoor air quality and environmental risk factors on adult asthma-related health outcomes in Chicago, IL.

Insung Kang, Anna McCreery, Parham Azimi...

https://pubmed.ncbi.nlm.nih.gov/36450925