Study of Beetroot Extract and Exercise to Support Heart, Physical, and Brain Health in Adults 75 Years and Older

What this Trial Is About

The trial investigates whether beetroot extract supplementation, alone or combined with a multicomponent physical exercise program, can improve cardiovascular health, functional ability, and cognitive function in adults aged 75 years and older. The study addresses the need for effective and affordable interventions to support healthy aging as the older adult population grows. It focuses on assessing the benefits of beetroots bioactive compounds and structured exercise adapted for very old adults. Participants are randomly assigned to one of four groups a placebo group receiving nitrate-depleted beetroot juice with no additional intervention a group receiving daily beetroot extract juice a group participating in a supervised then prescribed multicomponent exercise program combined with beetroot extract and a group doing the exercise program with placebo juice. The exercise includes strength, balance, mobility, and aerobic activities tailored to older adults abilities, with supervision during the first 6 weeks followed by unsupervised sessions for another 6 weeks. During the 12-week study, participants undergo assessments at baseline, 6 weeks, and 12 weeks measuring blood pressure, heart rate, cognitive tests, physical performance, strength, and quality of life. Additional monitoring includes glucose levels, blood nitrate and nitric oxide, and body composition. Researchers also evaluate medication use, sleep health, nutrition, and physical activity. The trial aims to provide evidence on the independent and combined effects of beetroot extract and exercise on health outcomes in this age group.

Beetroot Extract and Quality of Life in Adults Aged 75 and Over