Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
Healthy Volunteers
NCT06272045

Early Intervention to Promote Cardiovascular Health of Mothers and Children

Led by JHSPH Center for Clinical Trials · Updated on 2026-04-13

6618

Participants Needed

9

Research Sites

249 weeks

Total Duration

On this page

Sponsors

J

JHSPH Center for Clinical Trials

Lead Sponsor

N

National Heart, Lung, and Blood Institute (NHLBI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) is a cluster randomized clinical trial, funded by the National Heart Lung \& Blood Institute. The study is designed to test the effectiveness of home visiting intervention to promote cardiovascular health and reduce disparities in maternal and early childhood cardiovascular health. Sites, in partnership with evidence-based home visiting programs, are recruiting 6618 participants in total (i.e., 3309 mother-child dyads which includes 3309 mothers and 3309 children) from diverse community settings with a high burden of cardiovascular disease risk factors.

CONDITIONS

Official Title

Early Intervention to Promote Cardiovascular Health of Mothers and Children

Who Can Participate

Age: 18Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Currently enrolled in an evidence-based home visiting program participating in ENRICH
  • Pregnant with a single or multifetal pregnancy at or less than 34 weeks 0 days gestation
  • 18 years of age or older
  • Speak English or Spanish
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 9 locations

1

University of Alabama at Birmingham

Birmingham, Alabama, United States, 35294

Actively Recruiting

2

California Polytechnic State University

San Luis Obispo, California, United States, 93407

Actively Recruiting

3

University of Colorado

Aurora, Colorado, United States, 80204

Actively Recruiting

4

Northwestern University

Chicago, Illinois, United States, 60208

Actively Recruiting

5

Washington University in St. Louis

St Louis, Missouri, United States, 63130

Actively Recruiting

6

Wake Forest University

Winston-Salem, North Carolina, United States, 27109

Actively Recruiting

7

University of Pittsburgh

Pittsburgh, Pennsylvania, United States, 15260

Actively Recruiting

8

Pennsylvania State University

State College, Pennsylvania, United States, 16801

Actively Recruiting

9

Brown University/Lifespan

Providence, Rhode Island, United States, 02903

Actively Recruiting

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Research Team

L

Lori Burrell, MSW

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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Early Intervention to Promote Cardiovascular Health of Mothers and Children | DecenTrialz