Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT07356635

Cardiovascular Effects of Grieving

Led by University of South Florida · Updated on 2026-01-21

140

Participants Needed

1

Research Sites

71 weeks

Total Duration

On this page

Sponsors

U

University of South Florida

Lead Sponsor

A

Arizona State University

Collaborating Sponsor

AI-Summary

What this Trial Is About

Self-affirmation (SA) theory proposes that people are motivated to maintain a positive self-image of being worthy, stable, and capable. Self-affirmation (SA) manipulations have been shown to effectively increase self-worth as well as reduce cardiovascular reactivity while enhancing cardiovascular recovery in response to stress. While SA is discussed as a way to alleviate grief, its effect on cardiovascular reactivity (CVR) and recovery to grief recall has yet to be studied within laboratory settings. This study proposes an experimental design to examine how an in-lab manipulation promoting self-affirmation can improve patients' cardiovascular responses during and after a grief recall procedure. The investigators hypothesized that grief severity (a continuous variable) interacts with condition (a categorical variable with two levels, i.e., SA intervention vs. control) to predict CV reactivity and recovery as outcomes. Primary Objective 1: To investigate effects of self-affirmation intervention on cardiovascular responses among grieving participants during and after grief recall. Secondary Objective 1: To investigate the relationship of grief severity with psychological stress.

CONDITIONS

Official Title

Cardiovascular Effects of Grieving

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Individuals aged 18 and older who have experienced the death of family member and/or friend within the last 2 to 18 months.
  • Participants must also be fluent in English as all procedures will be conducted in English.
Not Eligible

You will not qualify if you...

- Individuals with a history of cardiovascular disease or disorders, those who report being pregnant, or are taking medication which may alter/affect cardiovascular and/or cognitive processes.

AI-Screening

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Trial Site Locations

Total: 1 location

1

University of South Florida, Psychology and Communication Sciences and Disorders Lab Building

Tampa, Florida, United States, 33620

Actively Recruiting

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Research Team

K

Kaiyuan Luo, BS, BA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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