Intrarenal resistive index after renal transplantation.
Maarten Naesens, Line Heylen
https://pubmed.ncbi.nlm.nih.gov/24521121Actively Recruiting
All Genders
ID01331668
Biobank Renal Transplantation at University Hospitals Leuven for Kidney Failure
Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2024-05-08
5000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are maintaining a biobank of human samples from kidney transplant donors and recipients to support future research projects. This observational study collects clinical data and biological specimens from individuals undergoing renal transplantation at the University Hospitals Leuven. The purpose is to enable translational research aimed at improving understanding and outcomes related to kidney failure and transplantation. The collected samples include biopsy tissue, peripheral blood, and urine from kidney transplant recipients and donors. These materials are stored for undefined future studies and translational research. All new kidney transplant recipients at the hospital are included as part of this collection effort. Participants provide samples and clinical information, which are prospectively gathered and stored. Researchers will monitor kidney transplant survival over an extended period, up to 50 years after transplantation. The study began in March 2004 and continues to collect data and samples to support long-term research goals related to kidney failure and transplantation outcomes.
CONDITIONS
Brief Title
BIOBANK Renal Transplantation University Hospitals Leuven
Who Can Participate
All Genders
Eligibility Criteria
You may qualify if you...
- Renal transplant recipients or donors
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
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Long-term Monitoring
Duration - Up to 50 years after transplantation
Participants who undergo routine care are observed, and clinical data and bio-specimens are collected for future research.
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Trial Site Locations
Total: 1 location
1
Department of Nephrology and Renal Transplantation - University Hospitals Leuven
Leuven, BE, Belgium, 3000
Actively Recruiting
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Research Team
M
Maarten Naesens, MD, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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Published Research Related To This Trial
A prospective, open-label, observational clinical cohort study of the association between delayed renal allograft function, tacrolimus exposure, and CYP3A5 genotype in adult recipients.
Dirk R J Kuypers, Hylke de Jonge, Maarten Naesens...
https://pubmed.ncbi.nlm.nih.gov/21118736Tacrolimus dose requirements and CYP3A5 genotype and the development of calcineurin inhibitor-associated nephrotoxicity in renal allograft recipients.
Dirk R J Kuypers, Maarten Naesens, Hylke de Jonge...
https://pubmed.ncbi.nlm.nih.gov/20526235Donor age and renal P-glycoprotein expression associate with chronic histological damage in renal allografts.
Maarten Naesens, Evelyne Lerut, Hylke de Jonge...
https://pubmed.ncbi.nlm.nih.gov/19762492Localization, etiology and impact of calcium phosphate deposits in renal allografts.
P Evenepoel, E Lerut, M Naesens...
https://pubmed.ncbi.nlm.nih.gov/19681815Expression of complement components differs between kidney allografts from living and deceased donors.
Maarten Naesens, Li Li, Lihua Ying...
https://pubmed.ncbi.nlm.nih.gov/19443638Calcium metabolism in the early posttransplantation period.
Pieter Evenepoel, Barbara Van Den Bergh, Maarten Naesens...
https://pubmed.ncbi.nlm.nih.gov/19261823Recovery of hyperphosphatoninism and renal phosphorus wasting one year after successful renal transplantation.
Pieter Evenepoel, Bjorn K I Meijers, Hylke de Jonge...
https://pubmed.ncbi.nlm.nih.gov/18922992Effects of CYP3A5 and MDR1 single nucleotide polymorphisms on drug interactions between tacrolimus and fluconazole in renal allograft recipients.
Dirk R Kuypers, Hylke de Jonge, Maarten Naesens...
https://pubmed.ncbi.nlm.nih.gov/18704002Tacrolimus exposure and evolution of renal allograft histology in the first year after transplantation.
M Naesens, E Lerut, B V Damme...
https://pubmed.ncbi.nlm.nih.gov/17608835