Actively Recruiting
Biomarkers for Exercise
Led by NYU Langone Health · Updated on 2026-03-31
30
Participants Needed
1
Research Sites
97 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The overarching objective is to examine the brain-based biological mechanistic pathway by which exercise exerts anxiolytic effects. The investigators will measure brain-derived markers of mitochondrial metabolism (acetyl-L-carnitine \[LAC\]) and inflammation (interleukin-6 \[IL-6\]) using innovative technology to isolate neuronal exosomes.
CONDITIONS
Official Title
Biomarkers for Exercise
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Between 18 and 50 years of age
- Currently sedentary (60 minutes or less of moderate intensity exercise per week for the past 3 months)
- Capable and willing to provide informed consent
- Primary psychiatric diagnosis of generalized anxiety disorder, social anxiety disorder, or panic disorder (for anxiety disorder group)
You will not qualify if you...
- Lifetime history of Bipolar I or II or any psychotic disorder
- Bulimia or anorexia in the past 3 months
- Alcohol or substance use disorder in the past 3 months
- Current major depressive disorder (past is allowed)
- Current neurologic disorder
- High current suicide risk with plan and intent requiring higher level care
- Participation in concurrent evidence-based therapy targeting anxiety and/or depression
- Risk for exercise due to active medical conditions such as heart conditions, lung disease, bone/joint problems, or seizures
- Women who are currently pregnant or planning pregnancy during the study
- Current psychiatric medication use
- Current substance abuse or positive urine toxicology screen (except recreational marijuana without cannabis use disorder)
- Active infection
- Non-psychiatric controls with current psychiatric condition assessed by MINI
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
NYU Langone Health
New York, New York, United States, 10016
Actively Recruiting
Research Team
K
Kristin Szuhany, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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