Actively Recruiting
An Exploratory Study Examining Biopsychosocial Markers of Anxiety and Depression
Led by Singula Institute · Updated on 2024-04-17
200
Participants Needed
1
Research Sites
474 weeks
Total Duration
On this page
Sponsors
S
Singula Institute
Lead Sponsor
S
Storyline Health
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research study is studying how thoughts, feelings, surroundings, and individual biology may contribute to why and how people experience anxiety or depression. We are trying to find out the wide variety of reasons that people may experience anxiety or depression, and why different people are helped by different forms of treatment. We are trying to determine why people stay in treatment, and what factors contribute to a positive or negative response to treatment. These reasons may be due to thoughts, feelings, beliefs, personality, biology, social support network, life events, and barriers to treatment. A wide range of information about factors that impact anxiety and depression will be included. These include, among others, measures of inflammation, hormone levels, behavior, spoken language, personality, medical history, social determinants of health, and attitudes toward mental health and its treatment. The study involves psychological and psychiatric treatments in the form of psychotherapy and medication management. The participant will be asked to set specific goals for study treatment, and to provide videos between sessions about relevant medication, emotional, and sleep factors in their life. In summary, this study will collect biological, psychological, and social factors that may play a role in anxiety and depression. This will inform both individual's diagnosis and treatment and will be used in a later set of analyses that can inform diagnosis and treatment for other individuals who share similar characteristics.
CONDITIONS
Official Title
An Exploratory Study Examining Biopsychosocial Markers of Anxiety and Depression
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 to 65 years of age
- Ability to understand and agree to all required tests and sign informed consent
- Diagnosis of Major Depression, single episode or recurrent, according to DSM-5 at enrollment
- May have comorbid Anxiety Disorders (Panic Disorder, Specific Phobia, Social Anxiety Disorder, Generalized Anxiety Disorder), Obsessive Compulsive Disorder, prior Post-Traumatic Stress Disorder, or Attention Deficit Hyperactivity Disorder as assessed by clinicians
- Agree to participate in clinical treatment with medication management and psychotherapy
You will not qualify if you...
- Serious, unstable illnesses including liver, kidney, gastrointestinal, lung, heart (including ischemic heart disease), hormone, neurological, immune, or blood diseases
- History of head trauma or stroke
- Clinically significant abnormal laboratory tests
- History of seizures without clear resolved cause or current use of medications lowering seizure threshold
- Use of opioid medication within the past 12 months
- Positive HIV test
- Current psychotic symptoms or diagnosis of schizophrenia or other psychotic disorders
- History of drug or alcohol dependency or abuse (except caffeine or nicotine) within 12 months; current illicit drug use within 2 weeks prior to screening
- Deemed by investigator to pose serious suicidal or homicidal risk
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Singula Institute, 353 Lexington Avenue (Room 600)
New York, New York, United States, 10016
Actively Recruiting
Research Team
J
Jen Tung, RN, MA
CONTACT
J
Jen Tung, RN, MA
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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