Study of Airway Tone and Reactivity Using Oscillometry in Adults Evaluated for Asthma

What this Trial Is About

Researchers are investigating whether airway resistance and pressure measured by a device called an Oscillometer are linked to abnormal results from a methacholine challenge test. They also want to see if these findings are related to body composition in adults with breathing difficulties being evaluated for asthma. This observational study is conducted by the University of Rochester and focuses on people referred for methacholine challenge testing due to dyspnea. Participants will undergo an oscillometry test using the tremoFlo C-100 Airwave Oscillometry System, which measures respiratory system impedance using the Forced Oscillation Technique. The main group includes subjects with breathing difficulties referred for methacholine challenge testing. There are no interventions or treatments administered, as this is an observational study focused on measuring lung function. During the study, participants will perform a breathing test and complete the oscillometry measurement approximately on day 1. Researchers will assess airway tone and hyper-reactivity through these tests. Participants must be able to speak and understand English and provide consent. The study will monitor lung function and airway resistance without any treatment changes, and participation lasts around the time needed for the tests on the first day.

Body Composition Related Evaluation of Airway Tone and Hyper-rEactivity Using Oscillometry