Actively Recruiting
Body Composition Related Evaluation of Airway Tone and Hyper-rEactivity Using Oscillometry
Led by University of Rochester · Updated on 2026-04-13
100
Participants Needed
1
Research Sites
17 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating whether airway resistance and pressure measured by a device called an Oscillometer are linked to abnormal results from a methacholine challenge test. They also want to see if these findings are related to body composition in adults with breathing difficulties being evaluated for asthma. This observational study is conducted by the University of Rochester and focuses on people referred for methacholine challenge testing due to dyspnea. Participants will undergo an oscillometry test using the tremoFlo C-100 Airwave Oscillometry System, which measures respiratory system impedance using the Forced Oscillation Technique. The main group includes subjects with breathing difficulties referred for methacholine challenge testing. There are no interventions or treatments administered, as this is an observational study focused on measuring lung function. During the study, participants will perform a breathing test and complete the oscillometry measurement approximately on day 1. Researchers will assess airway tone and hyper-reactivity through these tests. Participants must be able to speak and understand English and provide consent. The study will monitor lung function and airway resistance without any treatment changes, and participation lasts around the time needed for the tests on the first day.
CONDITIONS
Brief Title
Body Composition Related Evaluation of Airway Tone and Hyper-rEactivity Using Oscillometry
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Willingness to perform breathing test
- Must be able to speak and understand English
- Referred for Methacholine Challenge Test
You will not qualify if you...
- Unable to provide consent or perform oscillometry test
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo respiratory system impedance measurement using the Oscillometer as part of their evaluation for asthma.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
University of Rochester Medical Center
Rochester, New York, United States, 14620
Actively Recruiting
Research Team
P
Patrick Donohue, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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