Actively Recruiting
Bone Density and Vascular Calcifications Evolution After Renal Transplant
Led by University of Liege · Updated on 2024-12-18
50
Participants Needed
1
Research Sites
327 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The investigators project is based on: * Assessment of bone architecture by high resolution peripheral scanner (HRpQCT) and bone densitometry (DEXA); * The non-invasive detection of vascular calcifications (by abdominal CT scanner) and bone abnormalities associated with kidney transplantation, as well as the analysis of evolution over time; * Longitudinal evaluation of nephrological clinical parameters (glomerular filtration rate, number and type of rejections, immunosuppressive medications) as well as biological and urinary parameters of mineral metabolism (parathormone, sclerostin, bone alkaline phosphatase) depending on the type and severity of bone abnormalities; * The evaluation of these nephrological clinical parameters and of the biological parameters of mineral metabolism depending on the extent and evolution of vascular calcifications but also on bone morphology; * The study of possible relationships between bone mass and muscle mass (and functioning)
CONDITIONS
Official Title
Bone Density and Vascular Calcifications Evolution After Renal Transplant
Who Can Participate
Eligibility Criteria
You may qualify if you...
- At least 18 years old
- Recent kidney transplant patients (<3 months)
- Medical history available
- Biological parameters of the past year available
You will not qualify if you...
- Treatment with bisphosphonate, RANKL inhibitor or SERM with bone action in the last 3 months before the transplant
- Multiple organ transplant patients
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Centre Hospitalier Universitaire de Liège
Liège, Belgium, 4300
Actively Recruiting
Research Team
A
Antoine Bouquegneau
CONTACT
P
Pierre Delanaye
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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