Actively Recruiting
Explore the Bone Metabolism Characteristics of Premature Ovarian Insufficiency
Led by Shi Yun · Updated on 2024-06-25
60
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research investigates the bone metabolism characteristics in women with premature ovarian insufficiency (POI). The study focuses on evaluating specific markers such as serum tartrate resistant acid phosphatase-5b (TRACP-5b) and bone specific alkaline phosphatase (BALP), along with bone mineral density (BMD) measurements in various skeletal regions. Understanding these markers helps explore the impact of POI on bone health. Participants diagnosed with premature ovarian insufficiency will undergo diagnostic testing to assess bone metabolism. This includes measuring serum levels of TRACP-5b and BALP and evaluating BMD values at the lumbar spine (L1-L4), hips, and femoral necks. These assessments are performed on days 2 to 4 of menstruation or at enrollment for those with amenorrhea. During the study, participants provide blood samples and undergo bone density scans to evaluate bone health markers and BMD. Researchers measure these outcomes to better understand bone metabolic changes associated with POI. The study includes women aged 18 to 39 years who meet specific health and medical criteria. Participation involves one-time diagnostic assessments, with no drug treatments or extended interventions.
CONDITIONS
Brief Title
The Bone Metabolism Characteristics of Premature Ovarian Insufficiency
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients diagnosed by Western medicine with premature ovarian insufficiency
- Age between 18 and 39 years
- Patients who voluntarily participate in this study and sign an informed consent form
You will not qualify if you...
- Patients with congenital gonadal dysplasia or a family history of early menopause
- Patients with acquired organic lesions or ovarian surgery
- Patients who have taken artificial cycle therapy or endocrine therapy in the past three months
- Patients with serious primary diseases or mental disorders such as cardiovascular, cerebrovascular, liver, kidney, or hematopoietic system diseases
- Patients who are breastfeeding or pregnant
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo testing of serum levels of bone metabolic markers and bone mineral density measurements to explore bone metabolism characteristics.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
Dongzhimen Hospital, Beijing University of Chinese Medicine
Beijing, China
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here