Actively Recruiting
Study of Surgical Treatments for Long Bone Metastases Using Intramedullary Nail or Endoprosthetic Reconstruction
Led by Istituto Ortopedico Rizzoli · Updated on 2025-08-01
120
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
This research aims to collect ongoing data about the natural course of bone metastases and related bone events. It focuses on patients who have metastatic bone disease undergoing surgery for long bone fractures. The study evaluates clinical and biological factors to understand complications, functional outcomes, and survival differences in these patients. Participants receive surgical treatment either by intramedullary fixation using a nail inside the bone or endoprosthetic reconstruction replacement with a prosthesis. The study compares complication rates between these methods and by anatomic location. It also assesses functional results using the Musculoskeletal Tumor Society System and follows patients for up to 24 months after surgery. Throughout the study, researchers monitor clinical outcomes including surgery complications, functional status, and patient survival over two years. Data collected includes disease-specific, laboratory, and demographic information to understand factors affecting outcomes. This observational study involves no randomization or additional interventions beyond usual surgical care, and participation length varies depending on follow-up.
CONDITIONS
Brief Title
Bone Metastases Database of Patients Treated Surgically for Impending or Pathologic Fracture of Long Bones
Research Team
C
Costantino Errani, MD
D
Davide M Donati, MD
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