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ID03416959

Prospective Bone Metastases Database of Patients Treated Surgically for Long Bone Fractures

Led by Istituto Ortopedico Rizzoli · Updated on 2025-08-01

120

Participants Needed

1

Research Sites

N/A

Total Duration

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AI-Summary

What this Trial Is About

This research aims to collect ongoing data about the natural course of bone metastases and related bone events. It focuses on patients who have metastatic bone disease undergoing surgery for long bone fractures. The study evaluates clinical and biological factors to understand complications, functional outcomes, and survival differences in these patients. Participants receive surgical treatment either by intramedullary fixation (using a nail inside the bone) or endoprosthetic reconstruction (replacement with a prosthesis). The study compares complication rates between these methods and by anatomic location. It also assesses functional results using the Musculoskeletal Tumor Society System and follows patients for up to 24 months after surgery. Throughout the study, researchers monitor clinical outcomes including surgery complications, functional status, and patient survival over two years. Data collected includes disease-specific, laboratory, and demographic information to understand factors affecting outcomes. This observational study involves no randomization or additional interventions beyond usual surgical care, and participation length varies depending on follow-up.

CONDITIONS

Brief Title

Bone Metastases Database of Patients Treated Surgically for Impending or Pathologic Fracture of Long Bones

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with long bone metastases treated surgically with intramedullary nail or endoprosthetic reconstruction
Not Eligible

You will not qualify if you...

  • Patients with bone metastases of the spine

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Surgery and Immediate Post-operative Care

Duration - Up to 1 week

Participants undergo surgical treatment for long bone metastases with intramedullary nail or endoprosthetic reconstruction and receive immediate post-operative care.

1 surgical visit and approximately 1 week of post-operative visits

Post-operative Follow-up

Duration - Up to 24 months

Participants are followed after surgery to monitor clinical outcomes, functional results, and survival for up to 24 months.

Regular follow-up visits over 24 months

Trial Site Locations

Total: 1 location

1

Istituto Ortopedico Rizzoli

Bologna, Bologna, Italy, 40136

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Research Team

C

Costantino Errani, MD

D

Davide M Donati, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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