Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
ID06100263

Breast Cancer Resiliency Through Exercise Program (B-REP): Pilot Study

Led by University of Michigan Rogel Cancer Center · Updated on 2026-02-10

75

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating an exercise program designed to improve resiliency in Black breast cancer survivors who have completed primary treatment. This study uses a cross-sectional design followed by a two-arm randomized controlled trial comparing a 12-week supervised exercise intervention to a waitlist control group. The goal is to assess feasibility, adherence, program satisfaction, and various participant attitudes over 24 weeks. Participants in the exercise group follow an individualized resistance training program based on their 5-repetition maximum strength assessments. The program follows a progressive schedule of increased intensity and volume, with three sessions per week targeting upper and lower body muscles. The waitlist control group will complete assessments on the same schedule and later have the option to join online exercise sessions twice weekly for 12 weeks conducted via Zoom. During the study, participants will undergo assessments at baseline, after the 12-week intervention, and again 12 weeks post-intervention. Researchers will monitor retention, adherence to exercise, program fidelity, and participant satisfaction using questionnaires. The study includes follow-up evaluations up to 24 weeks to understand the sustained impact of the exercise program on participants' wellbeing and attitudes.

CONDITIONS

Brief Title

Breast Cancer Resiliency Through Exercise Program (B-REP)

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Women who self-identify as Black, African American, or Afro-Latina/e
  • Age 18 years or older
  • Confirmed diagnosis of Stage I to IIIA breast cancer
  • Completed primary treatment (surgery, chemotherapy, radiation) within 5 years prior to study start; hormonal therapy allowed
  • Currently exercising less than twice per week with resistance training
  • Able to speak and understand English
Not Eligible

You will not qualify if you...

  • Metastatic breast cancer
  • Medical conditions that prevent increasing exercise levels
  • Planned elective surgery during the study period
  • Pregnant or planning to become pregnant during the study period
  • Planning to move out of the United States during the study period
  • Currently enrolled in another exercise trial
  • Unable to pass exercise pre-screening or receive physician consent for increased physical activity

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Up to 24 weeks depending on group assignment

Participants in the intervention group complete a 12-week supervised individualized exercise program based on their baseline strength assessment. Participants aim for 3 resistance exercise sessions per week with progressive intensity and volume. Participants in the control group wait for 24 weeks without exercise intervention and complete the same assessments as the intervention group.

Regular assessments throughout the 24 weeks (visit frequency not specified)

Treatment

Duration - 12 weeks

After the initial 24-week waitlist period, control group participants are offered a 12-week guided online exercise program with sessions twice per week lasting 30 to 45 minutes each.

Twice-weekly online sessions

Trial Site Locations

Total: 1 location

1

University of Michigan

Ann Arbor, Michigan, United States, 48109

Actively Recruiting

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Research Team

C

Cancer AnswerLine

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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