Initial Predictors of Long-term Brain Resilience After Minor Ischemic Stroke: a Study Nested in the Brest Stroke Population-based Registry

What this Trial Is About

This research aims to develop a predictive model for quality of life more than four years after a minor ischemic stroke. It focuses on patients with mild stroke deficits, defined by a National Institute of Health Stroke Scale (NIHSS) score of 5 or less, to better understand long-term outcomes. The study will analyze both retrospective and prospective data from the Brest Stroke Registry, including patient characteristics collected shortly after stroke onset. Participants include patients who suffered a minor ischemic stroke over four years ago and are part of the Brest Stroke Registry. They may take part through telephone or face-to-face interviews with neurologists and clinical research technicians. Optional procedures include providing a saliva sample for DNA analysis and undergoing a cerebral MRI without contrast. The study will use questionnaires to assess quality of life and cognitive function, with data linked from hospital records and the registry. During the study, participants will complete quality of life and cognitive questionnaires and may provide saliva samples and have an MRI scan. Researchers will measure various outcomes such as quality of life scores, cognitive assessments, disability scales, depression and anxiety screening, and stroke recurrence. The study includes over four years of follow-up, with data collected at inclusion and the possibility of long-term monitoring of brain resilience after minor ischemic stroke.

BREMISS : Brain Resilience Minor Stroke Study