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Comparing Bupivacaine Liposomes and Bupivacaine for Ultrasound-Guided Costal Margin Block in Pain Relief After Laparoscopic Liver, Gallbladder, and Pancreatic Surgery
Led by Huazhong University of Science and Technology · Updated on 2026-07-06
60
Participants Needed
2
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are investigating the use of bupivacaine liposomes combined with bupivacaine versus bupivacaine alone for ultrasound-guided bilateral costal margin block CMB to manage postoperative pain in patients undergoing laparoscopic liver, gallbladder, and pancreatic surgery. This phase 4 randomized, single-blind clinical trial aims to evaluate if adding bupivacaine liposomes can better reduce opioid use after surgery compared to bupivacaine alone. The study addresses the need for effective regional analgesia techniques in upper abdominal surgeries, where current blocks may not fully relieve pain from anterior and outer abdominal wall incisions.
CONDITIONS
Brief Title
Bupivacaine Liposomes or Bupivacaine for CMB on Postoperative Analgesia in Laparoscopic Hepatobiliary Pancreatic Surgery
Research Team
L
Li Xu, MD
W
Wei Mei., MD
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