Study of Cognitive Function Development After Cannabis Abstinence in Adolescents Aged 15 to 18 with Cannabis Dependence or Harmful Use

What this Trial Is About

This research aims to assess how cognitive functions develop after achieving abstinence in adolescents diagnosed with cannabis dependence or harmful cannabis use. The study focuses on a group of young people aged 15 to 18 years, with abstinence confirmed through toxicological testing. The goal is to understand changes in brain function following cannabis abstinence during adolescence. Participants undergo neurocognitive assessments using a variety of tests, including the Trail Making Test, Auditory Verbal Learning Test, Stroop Test, Tower of London, and Continuous Performance Test-Identical Pairs. Urine toxicological assessments are used to confirm abstinence. The study observes cognitive performance changes over an 8-week period. During the study, participants will take these cognitive tests and provide urine samples to monitor abstinence. Researchers will measure changes in cognitive abilities such as attention, memory, and problem-solving. The main outcome is the change in performance on the Trail Making Test Part B after 8 weeks. Safety and adherence to abstinence are closely monitored throughout the study period, which lasts 8 weeks.

Cannabis Abstinence and Neurocognitive Assessment in Adolescence