Interactions between Sleep Apnea and Coronary Artery Disease on the Incidence of Sudden Cardiac Arrest: A Multi-Center Case-Control Study.
Eujene Jung, Hyun Ho Ryu, Young Sun Ro...
https://pubmed.ncbi.nlm.nih.gov/36579379Actively Recruiting
Age: 19Years - 79Years
All Genders
Healthy Volunteers
ID03700203
Cardiac Arrest Pursuit Trial With Unique Registration and Epidemiologic Surveillance
Led by Seoul National University Hospital · Updated on 2026-01-07
5340
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
S
Seoul National University Hospital
Lead Sponsor
K
Korean Center for Disease Control and Prevention
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are conducting a multicenter observational study to identify causes and risk factors of out-of-hospital cardiac arrest (OHCA) linked to chronic diseases and lifestyle behaviors. This study aims to develop a prediction model to identify high-risk populations and discover new biomarkers related to OHCA occurrence, survival, and disabilities. The study is based in 14 tertiary teaching hospital emergency departments in Korea and includes adults aged 19 to 79 years. The study involves two groups: cases and controls. Cases are adult patients who experienced EMS-treated OHCA and were transported to participating hospitals. These cases will be followed up by telephone at 1, 6, and 12 months after emergency department discharge to collect data on survival, disabilities, and quality of life. Controls are matched community members attending health screening centers for routine exams, selected in a 2:1 ratio to cases. Clinical data, survey data on lifestyle and comorbidities, and blood samples for biomarker development will be collected from both groups. Participants will provide extensive information including medical records, lifestyle surveys, and blood samples. Survivors among the OHCA cases will be monitored over one year to assess outcomes and quality of life. The main outcome measured is the number of OHCA cases enrolled during the study period. The study runs from September 2017 until December 2023, with ongoing data collection and follow-up, aiming to improve understanding and prediction of OHCA risks and outcomes.
CONDITIONS
Brief Title
Cardiac Arrest Pursuit Trial With Unique Registration and Epidemiologic Surveillance
Who Can Participate
Age: 19Years - 79Years
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Age between 19 and 79 years
- Experienced out-of-hospital cardiac arrest treated by emergency medical services
- Cardiac arrest event was not predicted for 24 hours before the incident
- Consent to provide personal information and blood samples for research
You will not qualify if you...
- Do not consent to personal information or blood sample collection for research
- Cardiac arrest caused by trauma, submersion, poisoning, hanging, suffocation, or other external causes
- Terminal condition with no further treatment plan due to malignancy, neurological, respiratory, rheumatic, hematologic, renal, or infectious diseases
- "Do not resuscitate" order issued by a doctor
- Receiving hospice care at time of cardiac arrest
- Pregnant patients
- Lack of family to provide information about the patient
- Patients transported after admission at another hospital
- Foreign patients
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
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Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Diagnostic Evaluation
Duration - Ongoing during enrollment period
Participants undergo clinical assessments and blood sample collection to evaluate health status and biomarkers related to cardiac arrest.
1 visit for cases transported to emergency departments; 1 visit for controls at health screening centers
Long-term Monitoring
Duration - Up to 12 months post discharge for cases; annual routine physicals for controls
Survived cardiac arrest cases are followed up by telephone to collect survival, disability, and quality of life outcomes at 1-month, 6-month, and 12-month after emergency department discharge. Controls are observed through their routine annual physical examinations.
3 telephone follow-up contacts for cases; 1 annual visit for controls
Trial Site Locations
Total: 1 location
1
Seoul National University Hospital
Seoul, South Korea, 110-744
Actively Recruiting
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Research Team
J
Jeong Ho Park
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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