Actively Recruiting

Early Phase 1
Age: 21Years +
All Genders
Healthy Volunteers
NCT05707871

Cardiovascular Effects of Very Low Nicotine Content Cigarettes

Led by Wake Forest University Health Sciences · Updated on 2025-10-03

49

Participants Needed

1

Research Sites

191 weeks

Total Duration

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AI-Summary

What this Trial Is About

The study is measuring Cardiovascular effects of very low nicotine content cigarettes on daily and non-daily smokers

CONDITIONS

Official Title

Cardiovascular Effects of Very Low Nicotine Content Cigarettes

Who Can Participate

Age: 21Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Self-reported cigarette smoking at least once in the past 30 days
  • 21 years old or older
  • Willingness to smoke research cigarettes or usual brand cigarettes during lab visit
  • Ability to speak, comprehend, and read English sufficiently to complete study procedures
Not Eligible

You will not qualify if you...

  • Self-reported diagnosis of cardiovascular diseases like coronary artery disease, stroke, peripheral artery disease, cardiac arrhythmia, pulmonary embolism, or blood clots in legs and arm in the past 3 months
  • Body temperature 100.4°F or higher
  • Unstable health conditions interfering with electrocardiogram (ECG) measurements
  • Self-reported diagnosis of hyperthyroidism or thyrotoxicosis
  • Currently pregnant or breastfeeding
  • Currently seeking treatment to quit smoking

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Wake Forest University Health Sciences

Winston-Salem, North Carolina, United States, 27157

Actively Recruiting

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Research Team

M

Maria Anwar, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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