Actively Recruiting

Age: 0 - 6Months
All Genders
NCT02061306

Celiac Disease Genomic Environmental Microbiome and Metabolomic Study

Led by Massachusetts General Hospital · Updated on 2026-04-17

500

Participants Needed

2

Research Sites

717 weeks

Total Duration

On this page

Sponsors

M

Massachusetts General Hospital

Lead Sponsor

U

University of Roma La Sapienza

Collaborating Sponsor

AI-Summary

What this Trial Is About

Celiac disease (CD) is a complex disease caused by eating gluten, a protein contained in wheat, rye, and barley. It is well known that many factors contribute to the development of CD, including the genes that you have and the foods that you eat. In the CDGEMM study, we will consider as many of these factors as possible and study how they each contribute to disease development. If the investigators find that any one factor, or combination of factors, increases the risk of developing CD, we will be able to apply this information and help prevent or detect disease in high-risk children in the future.

CONDITIONS

Official Title

Celiac Disease Genomic Environmental Microbiome and Metabolomic Study

Who Can Participate

Age: 0 - 6Months
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Newborns and infants less than 6 months of age who have not been introduced to solid foods (exclusive breast milk or formula diet)
  • First-degree relatives of patients affected with biopsy-proven CD
Not Eligible

You will not qualify if you...

  • Infants older than 6 months of age
  • Inability or unwillingness of legal guardian/representative to give written informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

MassGeneral Hospital for Children

Boston, Massachusetts, United States, 02114

Actively Recruiting

2

University of Roma La Sapienza

Rome, Italy, 00185

Actively Recruiting

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Research Team

V

Victoria Kenyon, MHA

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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