Actively Recruiting
Cognitive Function and Fatigue After Brain Abscess
Led by University of Oslo · Updated on 2025-07-04
50
Participants Needed
1
Research Sites
573 weeks
Total Duration
On this page
Sponsors
U
University of Oslo
Lead Sponsor
O
Oslo University Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Brain abscess is a focal bacterial or fungal infection of the brain. Treatment is neurosurgical drainage of pus followed by long-term antibiotic treatment. In spite of successful treatment of the infection, long-term cognitive problems or mental fatigue may ensue. The reason for this dysfunction may be a continuing inflammatory state or damage to brain tissue caused by the abscess. The investigators will evaluate these possibilities with the use of \[18F\]deoxyglucose-positron emission tomography (FDG-PET) and electroencephalography (EEG) in patients who have been treated for brain abscess and who experience cognitive problems and/or fatigue. FDG-PET may identify both inflammation and altered neuronal activity (the latter indicating damage to brain tissue), and EEG may identify altered neuronal activity, including changes in neuronal network activity.
CONDITIONS
Official Title
Cognitive Function and Fatigue After Brain Abscess
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients who have completed treatment for brain abscess and who agree to participate.
You will not qualify if you...
- Patients who cannot undergo neuropsychological investigation due to unconsciousness
- Patients who cannot undergo neuropsychological investigation, being mentally too ill
- Patients who suffer from dementia
- Patients who cannot undergo FDG-PET due to claustrophobia
- Patients who cannot undergo EEG due to panic attacks
- Age under 16.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Oslo University Hospital
Oslo, Norway, 0450
Actively Recruiting
Research Team
P
Peder H Utne
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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