Actively Recruiting

Age: 18Years +
All Genders
NCT05831631

Characterization of Circulating and Tumor-infiltrating Immune Cells in Malignant Brain Tumors

Led by Pietro Mortini, MD, Prof. · Updated on 2025-06-11

200

Participants Needed

1

Research Sites

365 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational study is to characterize the circulating leukocyte profile and the immune T cells distribution within the tumor in patients with malignant brain tumors and to correlate these findings with the oncological outcome. Participants will be subjected to blood sampling before surgery and for 12 months of follow-up. Additional sampling and analysis will be performed on tumor samples.

CONDITIONS

Official Title

Characterization of Circulating and Tumor-infiltrating Immune Cells in Malignant Brain Tumors

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients (≥18 years)
  • Able to express informed consent
  • With primary or secondary malignant brain tumor
  • Requiring neurosurgical treatment (radiosurgery, stereotactic biopsy, surgery)
Not Eligible

You will not qualify if you...

  • Patients who do not meet inclusion criteria.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

IRCCS San Raffaele Scientific Institute

Milan, Milan, Italy, 20132

Actively Recruiting

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Research Team

L

Laura Sincinelli

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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