The Risk of Growth in Patients With Non-malignant Brain Tumor: SeOuL cOhort of Brain Tumor MONitoring (SOLOMON) Study

What this Trial Is About

This research focuses on patients diagnosed with non-malignant brain tumors, such as meningioma, schwannoma, pituitary adenoma, and suspected non-malignant gliomas. The study aims to understand how these tumors grow naturally over time without immediate treatment, as many small and symptom-free tumors are often monitored rather than treated right away. The study includes a retrospective cohort from 1998 onward and a prospective cohort starting in 2022, both conducted at Seoul National University Hospital. The study collects data from patients who have undergone magnetic resonance imaging (MRI) scans to track tumor size and characteristics. The retrospective group includes patients with at least two MRIs spaced three months apart, while the prospective group consists of newly diagnosed patients who agree to participate and will have follow-up MRIs. No treatments such as radiotherapy or radiosurgery are given during observation unless necessary. Participants will undergo regular MRI scans to measure tumor volume and signal intensity over a period of up to 15 years. Researchers will analyze tumor growth rates and monitor which patients eventually require treatment. Data collection includes tumor volume changes and imaging characteristics, with follow-up continuing for those needing treatment. This long-term observation helps to better understand tumor behavior and guide future management strategies.

SeOuL cOhort of Brain Tumor MONitoring Study (SOLOMON)