A prospective study of the natural history of incidental meningioma-Hold your horses!
Maziar Behbahani, Geir Olve Skeie, Geir Egil Eide...
https://pubmed.ncbi.nlm.nih.gov/31832214/Actively Recruiting
Led by Seoul National University Hospital · Updated on 2024-12-03
3000
Participants Needed
1
Research Sites
N/A
Total Duration
This research focuses on patients diagnosed with non-malignant brain tumors, such as meningioma, schwannoma, pituitary adenoma, and suspected non-malignant gliomas. The study aims to understand how these tumors grow naturally over time without immediate treatment, as many small and symptom-free tumors are often monitored rather than treated right away. The study includes a retrospective cohort from 1998 onward and a prospective cohort starting in 2022, both conducted at Seoul National University Hospital. The study collects data from patients who have undergone magnetic resonance imaging MRI scans to track tumor size and characteristics. The retrospective group includes patients with at least two MRIs spaced three months apart, while the prospective group consists of newly diagnosed patients who agree to participate and will have follow-up MRIs. No treatments such as radiotherapy or radiosurgery are given during observation unless necessary. Participants will undergo regular MRI scans to measure tumor volume and signal intensity over a period of up to 15 years. Researchers will analyze tumor growth rates and monitor which patients eventually require treatment. Data collection includes tumor volume changes and imaging characteristics, with follow-up continuing for those needing treatment. This long-term observation helps to better understand tumor behavior and guide future management strategies.
CONDITIONS
SeOuL cOhort of Brain Tumor MONitoring Study (SOLOMON)
C
Chul-Kee Park, MD PhD
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Seoul National University Hospital
Lead Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 15 years
Participants with non-malignant brain tumors who do not require immediate treatment are observed and followed up with repeated MRI scans to monitor tumor growth and related factors.
Repeated MRI scans over time with timing determined by clinical needs
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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Lead Sponsor