Actively Recruiting

FEMALE
Healthy Volunteers
NCT04305808

Characterization of Vaginal, Urinary and Fecal Microbiomes in Women with Recurrent Urinary Tract Infections

Led by Hadassah Medical Organization · Updated on 2025-03-19

40

Participants Needed

1

Research Sites

230 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objectives are to evaluate whether variations in vaginal and/or urinary and/or fecal microbiome predispose postmenopausal women to recurrent cystitis. This will be explored using comparison of microbiome profiles between those with recurrent UTI compared to age-matched women without recurrent UTI.

CONDITIONS

Official Title

Characterization of Vaginal, Urinary and Fecal Microbiomes in Women with Recurrent Urinary Tract Infections

Who Can Participate

FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Postmenopausal status
  • Two or more documented, culture-positive urinary tract infections in the last six months or three or more infections in the last year (for patients)
  • Sterile urine cultures, normal urinalysis, and negative sexually-transmitted PCR urine assay (for control subjects)
Not Eligible

You will not qualify if you...

  • Neurogenic bladder condition
  • Known immunodeficiencies
  • Use of antibiotics or probiotics within the previous month
  • Known kidney stones or anatomical malformations
  • Prior history of urinary tract infections or other urologic abnormalities (for control subjects)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hadassah Medical Center

Jerusalem, Jerusalem, Israel, 9765422

Actively Recruiting

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Research Team

A

Ahinoam Lev-Sagie, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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