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Age: 7Years - 11Years
All Genders
Healthy Volunteers
ID07431021

Study on Lung Health and Inflammation in Children Aged 7 to 11 Comparing Physical Activity and Rest in Areas with Different Air Pollution Levels

Led by Queen Mary University of London · Updated on 2026-06-15

330

Participants Needed

1

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

Researchers are studying children aged 7 to 11 to understand how physical activity in areas with high air pollution affects lung health compared to rest in the same conditions. The study focuses on children attending schools classified by their air pollution levels, aiming to assess airway resistance and inflammation related to pollution exposure during physical activity versus sedentary behavior. Participants will be randomly assigned to either a 90-minute outdoor physical education PE lesson or a 90-minute outdoor science lesson, both conducted in their school playgrounds. During these sessions, children will wear activity monitors to track their movements, and air pollution levels will be recorded. Lung health assessments including height, weight, breathing tests, and nasal samples will be collected before and after the sessions. Children will be assessed on two separate days, with lung function and immune response tests conducted immediately after and 24 hours post-exposure. The study involves about four hours of total participation time, including health assessments and activity or rest sessions. Researchers will compare lung health changes between children in higher and lower pollution schools to understand the impact of air pollution during physical activity.

CONDITIONS

Brief Title

Children's Health, Respiratory Inflammation and Short-term Air Pollution

Research Team

J

James Scales, PhD

A

Abigail Whitehouse, MD,PhD

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