Actively Recruiting

Age: 30Years - 90Years
All Genders
ID03699228

China Nationwide Multi Center Big Data Study on Quantitative Computed Tomography and Health Status of Check-up Population

Led by Beijing Jishuitan Hospital · Updated on 2025-08-17

30000

Participants Needed

6

Research Sites

26 weeks

Total Duration

On this page

Sponsors

B

Beijing Jishuitan Hospital

Lead Sponsor

C

Chinese PLA General Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are conducting a nationwide, multi-center study in China to combine low dose chest CT scan data with Quantitative Computed Tomography (QCT) technology. The goal is to measure bone mineral density (BMD) of the spine, visceral adipose tissue (VAT), and liver fat content in people undergoing health checks. This study aims to assess how well QCT works in health screenings and to understand the rates of osteoporosis, obesity, and liver steatosis in the health check population across China. The study uses standard low dose chest CT scans commonly performed in health check centers to gather raw CT data. QCT then analyzes this data to quantify BMD, VAT, and liver fat content. These measurements help in diagnosing osteoporosis, evaluating obesity, and assessing liver steatosis without additional scanning procedures. The study collects this information from multiple centers throughout China, enhancing the data's breadth and reliability. Participants aged 30 to 90 years who undergo low dose chest CT scans as part of health checks are involved. The study monitors spinal volumetric bone mineral density as the primary outcome over two years. Secondary outcomes include measurements of visceral adipose tissue and liver fat, also tracked over two years. Researchers use this data to evaluate health status and disease prevalence. Pregnant women and individuals with metal implants in the CT scan area are excluded to ensure accurate imaging and safety.

CONDITIONS

Brief Title

China Health Big Data

Who Can Participate

Age: 30Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Health check subjects aged 30 to 90 years
  • Undergoing low dose chest CT scan as part of health check
Not Eligible

You will not qualify if you...

  • Pregnant women
  • Metal implant in the CT scan area

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - At baseline

Participants undergo low dose chest CT scans and quantitative computed tomography (QCT) assessments to measure bone mineral density, visceral fat, and liver fat content.

1 visit (in-person)

Long-term Monitoring

Duration - Up to 2 years

Participants are observed over time to evaluate the prevalence of osteoporosis, obesity, and liver steatosis based on imaging data collected.

Follow-up assessments may occur depending on study schedule

Trial Site Locations

Total: 6 locations

1

Wu Hu Yijishan Hospital

Wuhu, Anhui, China, 100035

Actively Recruiting

2

Beijing Jishuitan hospital

Beijing, Beijing Municipality, China, 100035

Actively Recruiting

3

The first affiliated hospital of Guiyang Medical University

Guiyang, Guizhou, China

Actively Recruiting

4

The first affiliated hospital of Zhengzhou University

Zhengzhou, Henan, China

Actively Recruiting

5

Hua Shan hospital

Shanghai, Shanghai Municipality, China

Actively Recruiting

6

Shanghai Ruijin hospital

Shanghai, Shanghai Municipality, China

Actively Recruiting

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Research Team

X

xiaoguang cheng, md

X

xiaoxia fu, md

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Published Research Related To This Trial

Association between high-density lipoprotein cholesterol and lumbar bone mineral density in Chinese: a large cross-sectional study.

Yongbing Sun, Xin Qi, Xuan Wang...

https://pubmed.ncbi.nlm.nih.gov/38267987

Association between total cholesterol and lumbar bone density in Chinese: a study of physical examination data from 2018 to 2023.

Yongbing Sun, Xin Qi, Xinbei Lin...

https://pubmed.ncbi.nlm.nih.gov/37865752

Opportunistic Screening Using Low-Dose CT and the Prevalence of Osteoporosis in China: A Nationwide, Multicenter Study.

Xiaoguang Cheng, Kaiping Zhao, Xiaojuan Zha...

https://pubmed.ncbi.nlm.nih.gov/33145809