Study of Circulating Non-coding RNA as Biomarkers in Acute Ischemic Stroke Patients Undergoing Endovascular Treatment

What this Trial Is About

This research focuses on acute ischemic stroke patients undergoing endovascular treatment. It aims to study the patterns of certain non-coding RNAscircular RNA, long non-coding RNA, and micro-RNAbefore and after treatment. These RNA types are being explored as potential biomarkers and regulators for stroke progression and prognosis, as well as their impact on the immune system following stroke. The study observes two groups of patients those before and those after endovascular treatment. It uses advanced genetic techniques like next-generation sequencing and quantitative real-time polymerase chain reaction to analyze the RNA expression. Researchers will identify specific RNA patterns and develop a predictive model to relate these findings to immune status and stroke outcomes. Participants will have their RNA levels measured and monitored for 90 days to assess changes over time. The study also examines the relationship between these RNAs and inflammatory factors, stroke-associated infections, and overall prognosis. This observational study does not involve experimental treatments but collects detailed biological data to better understand stroke recovery and treatment effects.

Circulating Non-coding RNA in Acute Ischemic Stroke With Endovascular Treatment (EVTRNA)