Actively Recruiting
Circulating Non-coding RNA in Acute Ischemic Stroke With Endovascular Treatment (EVTRNA)
Led by Nanjing First Hospital, Nanjing Medical University · Updated on 2026-04-09
300
Participants Needed
1
Research Sites
350 weeks
Total Duration
On this page
Sponsors
N
Nanjing First Hospital, Nanjing Medical University
Lead Sponsor
Z
Zhongda Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
EVTRNA is to analyze the differentiated expression pattern of circular RNA (circRNA), long non-coding RNA (lncRNA) and micro-RNA (miRNA) by next-generation sequencing in acute ischemic stroke patients before and/or after endovascular treatment. The candidate circRNA/lncRNA/miRNA will be verified as the biomarker and regulator for progression and prognosis of acute ischemic stroke with endovascular treatment. Further, the candidate non-coding RNA will be used to evaluate the effect of endovascular treatment on both peripheral and central immune after stroke.
CONDITIONS
Official Title
Circulating Non-coding RNA in Acute Ischemic Stroke With Endovascular Treatment (EVTRNA)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 years or older
- Confirmed acute ischemic stroke by diffusion-weighted imaging lesion on MRI and new lesion on brain CT scan
- Within 24 hours of symptom onset and treated with endovascular therapy
- Good performance status
- Signed an approved informed consent
You will not qualify if you...
- History of hemorrhagic infarction
- Chronic kidney or liver diseases
- Peripheral arterial occlusive disease
- Active malignant disease
- Inflammatory or infectious diseases
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Nanjing First Hospital, Nanjing Medical University
Nanjing, Jiangsu, China, 210006
Actively Recruiting
Research Team
J
Junshan Zhou, M.D
CONTACT
Q
Qiwen Deng, M.D
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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