Actively Recruiting

Age: 18Years +
FEMALE
NCT06430814

Clinical Biomarker of Paclitaxel-induced Peripheral Neuropathy

Led by University of Southern Denmark · Updated on 2025-09-02

188

Participants Needed

3

Research Sites

150 weeks

Total Duration

On this page

Sponsors

U

University of Southern Denmark

Lead Sponsor

O

Odense University Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

Investigation of which patients treated with paclitaxel have an increased risk of developing peripheral neuropathy.

CONDITIONS

Official Title

Clinical Biomarker of Paclitaxel-induced Peripheral Neuropathy

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Age > 18 years
  • Willing to give informed consent
  • Scheduled to receive neo-adjuvant or adjuvant paclitaxel treatment
  • Able to speak and understand Danish
  • Diagnosed with breast cancer
  • Paclitaxel nafive patients
Not Eligible

You will not qualify if you...

  • Neurodegenerative diseases such as neuropathy from other causes, previous stroke, or disc herniation
  • Type 1 or 2 diabetes
  • Pregnant
  • Breastfeeding
  • Relapse of cancer diagnosis
  • Diagnosed with human immunodeficiency virus (HIV)
  • Participation in other clinical trials changing paclitaxel dose or aiming to prevent neuropathic pain or reduce NFL levels (except use of cooling gloves)
  • Previous treatment with neurotoxic chemotherapy
  • Chronic pain from another cause
  • Metastatic cancer

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Odense University Hospital

Odense, Denmark, 5000

Actively Recruiting

2

University Hospital of Southern Denmark, Sønderborg

Sønderborg, Denmark, 6400

Actively Recruiting

3

University Hospital of Southern Denmark, Vejle

Vejle, Denmark, 7100

Actively Recruiting

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Research Team

D

Ditte Bork Iversen, MSc Pharm, PhD

CONTACT

T

Tore B. Stage, Prof

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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