Actively Recruiting

Age: 18Years +
All Genders
NCT05547607

Clinical and Diagnostic Features of Endocarditis

Led by University Hospital of Ferrara · Updated on 2026-05-01

500

Participants Needed

1

Research Sites

303 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The burden of endocarditis has changed in the last years due to an increase in percutaneous valve procedures offered to a more fragile, and old population. Therefore an update in epidemiology data is necessary. The Observational prospective multicenter study to characterize the cLinical ANd DiagnoStiC feAtures of endocarditis in the contemPorary Era, (ENDO-LANDSCAPE study) is an observational, multicenter and international study. The study has two arms: retrospective and prospective. The retrospective arm will involve collecting data from patients discharged with a diagnosis of endocarditis between 2016 and 2022. The data obtained in the retrospective arm of the study will be utilized in a power calculation to determine the sample size for the prospective arm of the study. In the prospective phase in every participating center, all patients referred for echocardiography to assess for endocarditis and those with established endocarditis independent of the screened request will be eligible. Patients will then be stratified according to the presence or abscence of endocarditis. Those with an established diagnosis of endocarditis will be prospectively followed for outcomes.

CONDITIONS

Official Title

Clinical and Diagnostic Features of Endocarditis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients above the age of 18 years.
  • All consecutive patients referred for echocardiography (transthoracic or transesophageal) to exclude endocarditis.
  • Patients diagnosed with endocarditis on echocardiography regardless of exam request.
Not Eligible

You will not qualify if you...

  • Patient's refusal to participate.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospital of Ferrara

Cona, Ferrara, Italy, 44124

Actively Recruiting

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Research Team

V

Veronica Lodolini, BsC

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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