Barts Heart Centre Registry Tracking Infective Endocarditis Patient Outcomes and Treatment Effectiveness

What this Trial Is About

This research registry focuses on Infective Endocarditis IE, a serious and rare heart infection with high morbidity and hospital mortality. It aims to assess the characteristics of IE in a specific population, evaluate the current use of imaging techniques, and monitor the application of European Society of Cardiology guidelines and their impact on patient outcomes. The registry will serve as a foundation for future research, including interventional studies aimed at improving diagnosis and management of IE. Participants include patients aged 16 and older admitted to or attending outpatient clinics at Barts Heart Centre with confirmed or suspected IE, including those with cardiac device-related endocarditis. The registry collects detailed epidemiological, demographic, microbiological, surgical, and outcome data over a 10-year period. This observational study does not involve drug or device interventions but gathers comprehensive clinical information to understand treatment effectiveness and patient prognosis. Participants are involved through data collection during their routine care, including clinical evaluations, imaging, and laboratory assessments. Researchers will measure mortality, morbidity, reinfection, and relapse rates over 10 years, and analyze relationships between infecting organisms, valve appearance, and pathological markers with clinical outcomes. The registry supports ongoing monitoring of patient health and helps inform future therapeutic trials to improve IE care.

Barts Endocarditis Research Registry