Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID06033014

Clinical Implementation of a Novel Decision Support Tool in Patients With Ischemic Heart Disease

Led by Rigshospitalet, Denmark · Updated on 2024-01-22

8000

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

R

Rigshospitalet, Denmark

Lead Sponsor

R

Region Capital Denmark

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are investigating the clinical usefulness of the PM-Heart algorithm (PMHeartIHD), a software tool designed to predict survival prognosis for patients hospitalized with ischemic heart disease (IHD) after coronary arteriography. The goal is to see if using this decision support system helps improve patient outcomes and reduce the risk of rehospitalization compared to standard treatment without the algorithm's input. Participants will be randomly assigned to one of two groups: one where the treating physician does not have access to the PM-Heart algorithm's one-year mortality prediction, and another where the physician receives this information to assist in treatment decisions. The algorithm offers a prognosis to support the physician's evaluation but does not give specific treatment instructions. The study monitors patients up to one year after randomization. During the study, researchers will track hospital readmissions, causes of death, length and number of hospital stays, cardiac investigations, follow-up consultations, medication use, and new cardiovascular events. They will also assess how the algorithm is received and used by medical staff, its usability, and related health economic impacts. The total participation time includes follow-up for one year after randomization.

CONDITIONS

Brief Title

Clinical Implementation of a Novel Decision Support Tool in Patients With Ischemic Heart Disease

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Hospitalized patients in one of the involved cardiology departments
  • Diagnosed with ischemic heart disease including stable, unstable angina, or myocardial infarction
  • Significant coronary artery lesions or diffuse coronary artery disease shown on invasive coronary angiography during admission
Not Eligible

You will not qualify if you...

  • Under 18 years of age
  • Living outside Denmark

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Up to 1 year

Participants are randomized to either receive the PM HeartIHD algorithm prediction available to their physician to assist in treatment decisions, or receive standard care without the algorithm's prediction.

Follow-up visits may occur during the year after randomization

Follow-up

Duration - Up to 1 year after treatment

Participants are monitored for readmissions, survival, cardiac investigations, and cardiovascular health for up to one year after randomization.

Visits include hospital and general practitioner check-ups occurring over the year

Trial Site Locations

Total: 1 location

1

Department of Cardiology, The Heart Centre, Rigshospitalet Copenhagen University Hospital.

Copenhagen Ø, Denmark, 2100

Actively Recruiting

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Research Team

H

Henning Bundgaard, Professor

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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