Actively Recruiting
A Clinical Study Evaluating the Safety and Efficacy of SKG0106 in Patients With Neovascular Age-related Macular Degeneration (nAMD)
Led by Youxin Chen · Updated on 2025-01-08
12
Participants Needed
3
Research Sites
108 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a clinical study to evaluate the safety, preliminary efficacy, immunogenicity of SKG0106 in subjects with nAMD.
CONDITIONS
Official Title
A Clinical Study Evaluating the Safety and Efficacy of SKG0106 in Patients With Neovascular Age-related Macular Degeneration (nAMD)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Voluntarily agree and able to sign informed consent before any study procedures
- Aged 50 years or older at screening
- Diagnosed with neovascular age-related macular degeneration as determined by the investigator
- Have active choroidal neovascularization lesions secondary to AMD
- Have shown response to anti-VEGF therapy prior to study treatment
You will not qualify if you...
- Have any active intraocular or periocular infection or inflammation in the study eye at baseline
- Have retinal pigment epithelial tear in the study eye at screening
- Have current vitreous hemorrhage in the study eye or history of vitreous hemorrhage within 4 weeks before baseline
- Have any condition that might limit visual acuity improvement in the study eye
- Have a history of or current retinal detachment in the study eye
- Have received any prior gene therapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Peking Union Medical College Hospital
Beijing, China
Actively Recruiting
2
Eye & ENT Hospital of Fudan University
Shanghai, China
Actively Recruiting
3
Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineXin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Shanghai, China
Actively Recruiting
Research Team
Y
Youchen Chen
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
3
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