Actively Recruiting

Phase 1
Phase 2
Age: 50Years - 80Years
All Genders
NCT06492863

Gene Therapy(FT-003) for Wet AMD

Led by Frontera Therapeutics · Updated on 2024-07-09

78

Participants Needed

1

Research Sites

269 weeks

Total Duration

On this page

Sponsors

F

Frontera Therapeutics

Lead Sponsor

T

Tianjin Medical University Eye Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to evaluate the safety, tolerability and efficacy of disposable vitreous injection of FT-003 in subjects with neovascular age-related Macular Degeneration (nAMD). The study was divided into two phases, Phase 1 dose escalation and Phase II dose expansion.

CONDITIONS

Official Title

Gene Therapy(FT-003) for Wet AMD

Who Can Participate

Age: 50Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Willing and able to follow study procedures
  • Male or female aged 50 to 80 years at signing the informed consent form
  • Clinically diagnosed with neovascular age-related macular degeneration (nAMD)
  • Presence of active choroidal neovascularization (CNV)
  • Best corrected visual acuity (BCVA) of the studied eye between 24 and 73 letters
Not Eligible

You will not qualify if you...

  • Presence of any other intraocular diseases in the studied eye that could affect vision improvement or require treatment during the study, as judged by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Tianjin Medical University Eye Hospital

Tianjin, Tianjin,China, China, 300392

Actively Recruiting

Loading map...

Research Team

X

Xinyan Li

CONTACT

M

Minghui Xue

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

TREATMENT

Number of Arms

3

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Gene Therapy(FT-003) for Wet AMD | DecenTrialz