Actively Recruiting
A Clinical Trial of MK-2828 in People With Kidney Disease (MK-2828-006)
Led by Merck Sharp & Dohme LLC · Updated on 2026-04-02
24
Participants Needed
3
Research Sites
24 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this trial is to measure what happens to 1 or 2 doses of MK-2828 in a person's body over time (pharmacokinetic or PK trial). Researchers want to learn if the PK of people with certain types of kidney disease is similar to the PK of healthy people.
CONDITIONS
Official Title
A Clinical Trial of MK-2828 in People With Kidney Disease (MK-2828-006)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants aged 24 to 85 years
- Generally good health except for renal impairment
- Participants with stable, chronic medical or psychiatric conditions may be included
- Severe renal impairment participants with estimated glomerular filtration rate (eGFR) below 30 mL/min and not on hemodialysis
- End-stage renal disease (ESRD) participants on stable outpatient intermittent high-flux hemodialysis for more than 3 months prior to study entry
You will not qualify if you...
- History of any illness other than renal impairment that could affect study results or pose additional risk
- Healthy matched controls with clinically significant endocrine, gastrointestinal, cardiovascular, hematological, hepatic, immunological, renal, respiratory, genitourinary, or major neurological diseases
- Participants with recent or complicated medical events not approved by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Panax Clinical Research ( Site 0003)
Miami Lakes, Florida, United States, 33014
Actively Recruiting
2
Floridian Clinical Research ( Site 0001)
Miami Lakes, Florida, United States, 33016
Actively Recruiting
3
Orlando Clinical Research Center ( Site 0002)
Orlando, Florida, United States, 32809
Actively Recruiting
Research Team
T
Toll Free Number
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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