Differential effects of insular and ventromedial prefrontal cortex lesions on risky decision-making.
L Clark, A Bechara, H Damasio...
https://pubmed.ncbi.nlm.nih.gov/18390562/Actively Recruiting
Led by University Hospital, Grenoble · Updated on 2024-01-17
400
Participants Needed
1
Research Sites
N/A
Total Duration
This research focuses on studying cognitive difficulties linked to specific brain injuries and their locations. The aim is to build a large database of patient behavioral responses during cognitive tasks to better understand brain function. The study includes patients with focal brain lesions caused by stroke or surgical removal of brain tissue, which affect functions like attention, language, memory, decision-making, and executive function. Participants will undergo cognitive tasks that assess various higher brain functions such as attention, language, memory, decision-making, and executive skills. These tasks are observational and involve patients who have had focal brain injuries either from stroke or brain surgery. The study collects data during routine visits scheduled at 3, 6, 12, or 24 months after the brain lesion, with up to four sessions lasting about two hours each. During the study, participants will perform cognitive tasks while their behavioral performance, including reaction times and error rates, is recorded. These assessments happen during routine follow-up visits over two years. Researchers will analyze this data to explore links between brain structures and cognitive functions. The total participation may involve up to four sessions, each lasting approximately two hours, to track changes over time and better understand cognitive deficits after brain injury.
CONDITIONS
Cognitive Function Assessment in Patients With Focal Brain Injury
P
Philippe Kahane, MD, PhD
J
Julien Bastin, PhD
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University Hospital, Grenoble
Lead Sponsor
Grenoble Institut des Neurosciences
Collaborating Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 24 months post lesion
Participants complete cognitive tasks assessing attention, language, memory, decision-making, and executive functions during routine visits over two years following their brain injury.
Up to 4 routine visits at 3, 6, 12, or 24 months post lesion, each lasting about two hours
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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Lead Sponsor
Grenoble Institut des Neurosciences
Collaborating Sponsor