Actively Recruiting

Age: 18Years +
All Genders
NCT05014399

Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy

Led by Joseph McCollom · Updated on 2025-06-11

60

Participants Needed

1

Research Sites

523 weeks

Total Duration

On this page

Sponsors

J

Joseph McCollom

Lead Sponsor

I

Indiana University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this research study is to see how the brain changes in patients receiving chemotherapy (cytotoxic drug) treatment for colon or rectal cancer at Parkview Cancer Institute. This information will be used to identify helpful tests to diagnose individuals at risk for developing difficulties with thinking and memory due to their cancer treatments.

CONDITIONS

Official Title

Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed written informed consent according to Good Clinical Practice and HIPAA before study procedures
  • Histologically-confirmed colorectal tumor
  • Patients planned to receive cytotoxic chemotherapy including Capecitabine, Oxaliplatin, 5 fluorouracil, and Irinotecan
  • No prior cytotoxic chemotherapy before enrollment
Not Eligible

You will not qualify if you...

  • Prior anti-cancer chemotherapy, radiotherapy, immunotherapy, or investigational agents
  • Mental incompetence preventing survey completion
  • Pregnant or breastfeeding
  • Known brain metastases
  • Non-English speaking
  • Diagnosed neuro-cognitive disorders including traumatic brain injuries, Alzheimer's disease, Parkinson's disease, Huntington's disease, and Creutzfeldt-Jakob disease
  • Deemed inappropriate for study participation by study PI or coordinator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Parkview Cancer Institute

Fort Wayne, Indiana, United States, 46845

Actively Recruiting

Loading map...

Research Team

J

Joseph McCollom, DO

CONTACT

E

Emily Powell, PHD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy | DecenTrialz