Cognitive Function Before and After Surgery for Frontal or Temporal Skull Base Meningioma

What this Trial Is About

This research aims to evaluate long-term cognitive outcomes in patients undergoing surgery to remove a meningioma located in the frontal or temporal lobes of the brain. The study focuses on understanding how cognitive function changes before and after surgery through standardized cognitive tests. It includes adults aged 18 to 89 who are scheduled for meningioma resection by either craniotomy or an endoscopic endonasal approach. Participants will receive standard cognitive testing conducted by a speech-language pathology team at three time points before surgery baseline, six weeks after surgery, and one year after surgery. These tests include the Repeatable Battery for the Assessment of Neuropsychological Status RBANS, the Montreal Cognitive Assessment MoCA, PROMIS-29, and Neuro-QoL Cognitive Functions to assess various aspects of cognition. Throughout the study, patients will be monitored for changes in overall cognitive function as the primary outcome at one year after surgery. Secondary outcomes include cognitive function differences based on surgical approach and tumor location at the same time point. Participants are expected to attend follow-up visits for cognitive assessments and complete questionnaires to help researchers understand post-surgical cognitive changes over time.

Cognitive Status After Removal of Skull Base Meningioma