Actively Recruiting
Combination of Nerve Blocks and Local Infiltration Analgesia in Knee Arthroplasty
Led by Region Skane · Updated on 2026-05-08
200
Participants Needed
1
Research Sites
77 weeks
Total Duration
On this page
Sponsors
R
Region Skane
Lead Sponsor
G
Greta and Johan Kock Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aim of this clinical randomized trial is to compare local infiltration analgesia (LIA) alone versus the combination of LIA with saphenous nerve (SN) block, block of the nerve to vastus medialis (NVM), and anterior femoral cutaneous nerve (AFCN) block in participants undergoing total knee arthroplasty (TKA). The primary outcome is pain intensity, measured using the Numerical Rating Scale (NRS) at multiple time points after surgery. Secondary outcomes include opioid consumption, time to mobilization, postoperative nausea and vomiting, length of hospital stay, neurological complications and differences in opioid consumption and NRS pain scores between general and spinal anesthesia.
CONDITIONS
Official Title
Combination of Nerve Blocks and Local Infiltration Analgesia in Knee Arthroplasty
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Undergoing primary unilateral total knee arthroplasty
You will not qualify if you...
- Pregnancy
- Coagulopathy or other bleeding disorder that precludes regional anesthesia
- Allergy to local anesthetics
- Inability to understand spoken and written Swedish
- Unwillingness to participate in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Anaesthesiology, Trelleborg Hospital
Trelleborg, Sweden
Actively Recruiting
Research Team
F
Fredrik Fellert, MD
CONTACT
A
Andreas Ekman, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here