Evaluating Oral Midazolam Alone and Combined with Ibuprofen or Ketamine for Better Venipuncture Comfort in Children Undergoing Day Surgery

What this Trial Is About

This research aims to compare the effects of different oral premedication regimens on how well children tolerate venipuncture during ambulatory surgery. The study focuses on pediatric patients aged 4 to 12 years undergoing elective day-case procedures. Researchers want to find the best premedication strategy to reduce distress and improve cooperation when placing intravenous lines in children before anesthesia. Participants are randomly assigned to one of three groups oral midazolam alone, oral midazolam combined with ibuprofen, or oral midazolam combined with ketamine. Each medication regimen is given as a single oral dose about 20 minutes before the child is taken to the operating room for anesthesia induction. If the premedication is insufficient or venipuncture fails, a rescue inhalational induction method will be used to ensure safety. Throughout the study, children will be observed during intravenous cannulation to assess venipuncture tolerance using behavioral and pain scales. Anxiety levels will be measured before and after premedication. Researchers will also evaluate the success of venipuncture, the time taken to establish intravenous access, and satisfaction levels of parents and anesthesiologists. Participation includes one premedication dose and monitoring during surgery preparation, with safety procedures in place throughout the process.

Comparative Assessment of Oral Premedication Regimens in Pediatric Ambulatory Surgery