Actively Recruiting

Phase Not Applicable
Age: 40Years - 70Years
All Genders
ID06918847

Comparative Effectiveness of Myofacial Release vs Cupping Therapy on Quality of Life in Restless Leg Syndrome With Knee Osteoarthritis A Randomized Controlled Trial

Led by Dow University of Health Sciences · Updated on 2025-10-07

54

Participants Needed

1

Research Sites

34 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate how effective Myofascial Release and Dynamic Cupping Therapy are in improving the quality of life for people with Restless Leg Syndrome who also have knee Osteoarthritis. The study is a randomized controlled trial conducted at a physiotherapy outpatient department, where participants are carefully selected using specific criteria for Restless Leg Syndrome. Participants will be randomly assigned to one of two groups. Group A will receive Myofascial Release therapy, involving a 15-minute session applying pressure with the therapist's thumb on the calf muscle while the patient lies face down. Group B will undergo Dynamic Cupping Therapy for 10 minutes, where cups are applied and moved over the calf and hamstring areas with lubricant to create negative pressure. Both groups will also receive cryotherapy and passive stretches for the lower limbs as standard treatment. Treatments will be given in 12 sessions over 4 weeks on alternate days. During the study, participants will be assessed at the start and after the 4-week treatment period using several tools including the Pittsburgh Sleep Quality Index, Visual Analog Scale for pain, Restless Leg Syndrome Quality of Life questionnaire, International Restless Leg Syndrome Study Group Rating Scale, and passive straight leg raise test. A physical therapist unaware of the treatment type will conduct assessments. This study will monitor changes in symptoms and quality of life to understand the impact of these therapies.

CONDITIONS

Brief Title

Comparative Effectiveness of Myofacial Release vs Cupping Therapy on Quality of Life in Restless Leg Syndrome With Knee O.A.

Who Can Participate

Age: 40Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Knee Osteoarthritis grade 2, 3, or 4 by Kellgren Lawrence classification
  • Bilateral or unilateral knee Osteoarthritis
  • Age between 40 and 70 years
  • Meets International Restless Leg Syndrome Study Group criteria for Restless Leg Syndrome
Not Eligible

You will not qualify if you...

  • Cognitive dysfunction
  • Rheumatoid arthritis
  • Neurological disorders
  • Medical conditions including cardiovascular disease, severe psychiatric illness, or pregnancy

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Treatment

Duration - 4 weeks

Participants receive either myofascial release or dynamic cupping therapy targeting the calf and hamstrings to improve symptoms of restless leg syndrome and knee osteoarthritis.

Multiple treatment sessions over 4 weeks

Trial Site Locations

Total: 1 location

1

Dow Institute of Physical Medicine and Rehabilitation

Karachi, Sindh, Pakistan, 74200

Actively Recruiting

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Research Team

S

Syeda Tooba Batool, doctor of physical therapy

D

Dr. Farhan Ishaque Khan, Ph.D.

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Published Research Related To This Trial

Restless legs syndrome: An overview of pathophysiology, comorbidities and therapeutic approaches (Review).

Andrei Vlasie, Simona Corina Trifu, Cristiana Lupuleac...

https://pubmed.ncbi.nlm.nih.gov/35069866