Comparing the Antiplaque Efficacy of Titania Nanoparticle Infused Fluoride Varnish vs Conventional Fluoride Varnish in Fixed Orthodontic Patients-A Triple Blind Randomised Controlled Trial

What this Trial Is About

This research aims to compare the antiplaque effects of a novel fluoride varnish infused with titania nanoparticles derived from moringa oleifera leaves extract against a conventional fluoride varnish in patients undergoing fixed multibracket orthodontic treatment. The study focuses on dental plaque accumulation and evaluates the potential benefits of nanoparticle-enhanced fluoride varnishes in dental care. Participants are randomly assigned to one of two groups: Group A receives the conventional fluoride varnish, while Group B receives the fluoride varnish infused with titania nanoparticles. Both varnishes are applied topically to the teeth of fixed orthodontic patients. The study is designed as a triple-blind randomized controlled trial to ensure unbiased assessment. Over six months, researchers will measure the plaque inhibitory effects using a modified plaque index, along with plaque bacterial load and pH levels. Participants will undergo regular dental assessments to monitor these outcomes. The involvement period includes treatment application and follow-up to evaluate differences in plaque accumulation between the two varnishes.

Comparing the Antiplaque Effects of Novel Titania Nanoparticle Infused Fluoride Varnish vs Conventional Fluoride Varnish in Fixed Orthodontic Patients.