Comparing Symptom Relief Between Microwave Ablation and Uterine Artery Embolization for Adenomyosis in Women Aged 30 to 55

What this Trial Is About

Researchers are evaluating symptom improvement in women with adenomyosis by comparing two minimally invasive treatments uterine artery embolization UAE and ultrasound-guided percutaneous or transvaginal microwave ablation. Adenomyosis is a benign condition causing pain and bleeding that can significantly affect womens lives. Traditional treatment often involved hysterectomy, but this study explores less invasive options to preserve the uterus and reduce complications. The study randomly assigns women to either microwave ablation, performed with a needle antenna guided by ultrasound or CT imaging, or uterine artery embolization, where a catheter delivers particles to block blood flow to adenomyotic tissue. Microwave ablation is done under anesthesia with a small incision or vaginally, while embolization is performed with pain management and catheterization of the femoral artery. Both treatments aim to reduce symptoms, and participants are followed up at 2 and 6 months post-treatment, with an extended follow-up for symptom recurrence. Participants will complete validated questionnaires assessing symptom severity and quality of life before and after treatment. Pain levels, menstrual blood loss, medication use, hospitalization time, and acceptability of treatment are monitored. Blood tests and MRI scans assess physical changes and ovarian function. The study lasts beyond 6 months, with long-term yearly follow-up to evaluate ongoing effects and symptom recurrence. This comprehensive monitoring ensures detailed assessment of both treatment approaches.

Comparing Efficacy of Microwave Vs Embolization Treatment for Adenomyosis