Actively Recruiting

Phase Not Applicable
Age: 30Years - 55Years
FEMALE
NCT04209127

Comparing Efficacy of Microwave Vs Embolization Treatment for Adenomyosis

Led by Karolinska Institutet · Updated on 2024-11-20

70

Participants Needed

1

Research Sites

301 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Single blinded randomized controlled study of symptom improvement after uterine artery embolization (UAE) versus ultrasound guided percutaneous/transvaginal microwave ablation, evaluated by validated questionnaires. Adenomyosis is a benign condition causing pain and bleeding disorders in many women. Hysterectomy has historically been the golden standard for treatment as well as (postoperatively) diagnosis of the disease. In accordance with refined diagnostic tools such as ultrasound and/or MRI, minimally invasive treatments for adenomyosis are being explored. We plan to compare two minimally invasive techniques: embolization of the uterine artery (a commonly used procedure) and microwave ablation of adenomyotic tissue (previously only in clinical use in China).

CONDITIONS

Official Title

Comparing Efficacy of Microwave Vs Embolization Treatment for Adenomyosis

Who Can Participate

Age: 30Years - 55Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy women aged 30-55 with symptomatic adenomyosis
  • Premenopausal
  • Adenomyosis diagnosted by TVUS
  • Willing to comply with protocol
Not Eligible

You will not qualify if you...

  • Body Mass Index >35
  • Treatment with anticoagulant/bleeding disorder
  • Contraindication for UAE or general anesthesia

AI-Screening

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Trial Site Locations

Total: 1 location

1

Danderyd Hospital

Stockholm, Sweden, 182 88

Actively Recruiting

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Research Team

K

Klara Hasselrot, MD PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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