Actively Recruiting

Phase Not Applicable
Age: 50Years - 85Years
All Genders
ID06770153

Comparison Between the Use of the Tensioner and Standard Surgical Technique for Ligament Balancing of Total Knee Prostheses

Led by Istituto Ortopedico Rizzoli · Updated on 2026-01-26

200

Participants Needed

1

Research Sites

8 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are comparing two surgical techniques for ligament balancing in patients receiving primary posterior-stabilized total knee arthroplasty (TKA) using the same prosthetic model. The study aims to evaluate post-operative joint laxity using stress radiographs and clinical scores in two patient groups, one treated with the standard technique and the other with the intraoperative use of a tensioner. This comparison is conducted across two specialized centers to assess differences in outcomes. The study involves two groups: one undergoing standard TKA implantation with ligament balancing performed without a tensioner, and the other using the TEMIS DePuy tensioner to assist with balancing following the gap-balancing technique. Both groups receive the same cemented Attune PS mobile plate prosthesis model. The trial is randomized and does not involve blinding. Participants will have radiographic images taken at baseline, and again at 3, 6, and 12 months after surgery to measure post-operative laxity. Additional assessments include measuring the Hip-Knee-Ankle angle and using a visual analogue scale at the same time points. Patients must attend all scheduled follow-up visits for these evaluations. The total participation duration spans at least 12 months after surgery, allowing researchers to monitor recovery and knee function over time.

CONDITIONS

Brief Title

Comparison Between the Use of the Tensioner and Standard Surgical Technique for Ligament Balancing of Total Knee Prostheses

Who Can Participate

Age: 50Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male and female subjects candidates for primary cemented total knee prosthesis model Attune PS mobile plate DePuy
  • Patients who have the psychophysical ability to undergo the operation and all scheduled check-ups including radiological tests
  • Patients who have signed the informed consent approved by the Ethics Committee
  • Patients aged between 50 and 85 years
Not Eligible

You will not qualify if you...

  • Social conditions preventing participation in all study phases (e.g., homelessness, restrictions on personal freedom)
  • Deep venous insufficiency of the lower extremities or personal/family history of deep venous thrombosis or pulmonary embolism
  • History of erysipelas in the lower extremities
  • Neurological or psycho-cognitive disorders
  • Post-traumatic arthrosis
  • Prior prosthetic surgery or arthrodesis on a lower limb joint
  • Axial knee deformities greater than 15 degrees
  • Pregnant female patients
  • Rheumatic diseases

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surgery and Immediate Post-operative Care

Duration - Up to 1 week or until discharge

Participants undergo total knee prosthesis surgery using either the tensioner or standard surgical technique for ligament balancing, followed by immediate post-operative care.

1 surgical visit and daily post-operative visits during hospital stay

Post-operative Follow-up

Duration - 12 months

Participants attend scheduled follow-up visits for clinical assessments and radiographical imaging to monitor recovery and outcomes after surgery.

Visits at baseline, 3 months, 6 months, and 12 months post-surgery

Trial Site Locations

Total: 1 location

1

IRCCS Istituto Ortopedico Rizzoli

Bologna, Italy, 40136

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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