Actively Recruiting

Age: 12Years - 65Years
All Genders
NCT07174219

Clinical-instrumental Evaluation and Assessment of Return to Sports Activity in Patients Surgically Treated for Isolated "Stener-like" Lesions of the Medial Collateral Ligament (MCL) or in the Context of Multiligament Injuries and Articular Fractures

Led by Stefano Zaffagnini · Updated on 2025-09-16

43

Participants Needed

1

Research Sites

255 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The knee is a complex joint stabilized by four main ligaments: the anterior and posterior cruciate ligaments and the medial and lateral collateral ligaments. Multiligamentous knee injuries involve at least two ligaments and usually result from high-energy trauma, causing significant functional limitations. One specific injury is the "Stener-like" lesion of the medial collateral ligament (MCL), characterized by an avulsion at its distal tibial insertion with interposition of tendons from the pes anserinus, which prevents natural healing. This lesion often occurs with other ligament or bone injuries and requires surgical treatment. Diagnosis is clinical, supported by MRI to confirm the distal lesion and tendon interposition. Despite its importance, literature on this injury is scarce, with only a few studies and case reports, often limited by small sample sizes and lack of standardized follow-up assessments. Due to the rarity and complexity of these injuries, there is a need for a comprehensive clinical study with standardized evaluations to improve understanding and develop standardized surgical treatments for isolated and associated Stener-like MCL lesions.

CONDITIONS

Official Title

Clinical-instrumental Evaluation and Assessment of Return to Sports Activity in Patients Surgically Treated for Isolated "Stener-like" Lesions of the Medial Collateral Ligament (MCL) or in the Context of Multiligament Injuries and Articular Fractures

Who Can Participate

Age: 12Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients of both male and female sex
  • Patients aged between 12 and 65 years at the time of surgery
  • Patients who underwent surgical re-insertion of the distal insertion of the medial collateral ligament starting from 01/01/2020 until 12/31/2027
  • Patients who had isolated distal medial collateral ligament re-insertion surgery or the same procedure combined with other surgeries on the same knee
  • Patients who have given consent to participate in the study
  • Patients who underwent preoperative imaging confirming distal medial collateral ligament injury (MRI for ligament injuries; X-ray and/or CT for fractures)
Not Eligible

You will not qualify if you...

  • Previous fractures of the same limb treated surgically
  • Age under 12 years or over 65 years at time of surgery
  • Patients who have not provided informed consent
  • Patients who are no longer contactable
  • Patients who have not engaged in sports activity in the 2 years prior to surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

IRCCS Rizzoli Ortopedic Institute

Bologna, Bologna, Italy, 40136

Actively Recruiting

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Research Team

S

stefano zaffagnini

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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