Actively Recruiting

Phase 1
Age: 20Years - 60Years
All Genders
NCT07429448

Comparison Of Clinical Outcomes of Intraperitoneal Bupivacaine Instillation Versus Placebo as Preemptive Analgesia in Patients Undergoing Open Appendectomy

Led by Sardar Umer Rehman · Updated on 2026-02-24

60

Participants Needed

1

Research Sites

26 weeks

Total Duration

On this page

Sponsors

S

Sardar Umer Rehman

Lead Sponsor

S

Services Institute of Medical Sciences, Pakistan

Collaborating Sponsor

AI-Summary

What this Trial Is About

To compare the clinical outcomes of intraperitoneal bupivacaine instillation vs placebo as preemptive analgesia in patients undergoing open appendectomy

CONDITIONS

Official Title

Comparison Of Clinical Outcomes of Intraperitoneal Bupivacaine Instillation Versus Placebo as Preemptive Analgesia in Patients Undergoing Open Appendectomy

Who Can Participate

Age: 20Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients presenting to the emergency department undergoing open appendectomy.
Not Eligible

You will not qualify if you...

  • Patients undergoing interval appendectomy or with perforated appendix confirmed by examination or ultrasound.
  • Uncontrolled medical diseases such as diabetes with blood sugar over 200 mg/dl or hypertension with blood pressure over 140/90.
  • History of chronic kidney or liver disease, psychiatric illness, or active peptic ulcer disease.
  • Alcoholics.
  • History of chronic pain or current use of analgesic medications.
  • Pregnant females.
  • History of allergy to bupivacaine or ketorolac.
  • Children, adolescents, and patients with mental illness.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Services Institute of Medical Sciences/ Services Hospital Lahore

Lahore, Punjab Province, Pakistan, 54000

Actively Recruiting

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Research Team

D

Dr Sardar Umar Rehman, MBBS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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Comparison Of Clinical Outcomes of Intraperitoneal Bupivacaine Instillation Versus Placebo as Preemptive Analgesia in Patients Undergoing Open Appendectomy | DecenTrialz