Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
Healthy Volunteers
ID07031856

Comparison of Clinical Performance of Partial Restorations Fabricated With Three-Dimensional Printer and CAD-CAM: A Split-Mouth Randomized Clinical Trial

Led by Cukurova University · Updated on 2026-04-02

12

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This clinical trial focuses on adults aged 18 to 65 who have dental hard tissue loss or require replacement restorations on two teeth. It aims to compare two types of partial dental restorations—those made with CAD-CAM technology and those produced using a 3D printer—based on criteria set by the FDI World Dental Federation. Researchers want to determine if there is a difference in clinical performance between these two dental restoration methods. Participants will be randomly assigned in a split-mouth design to receive a CAD-CAM partial restoration on one tooth and a 3D printed partial restoration on the other tooth. This allows direct comparison within the same individual. The study includes two groups: one with restorations made by 3D printing and the other with CAD-CAM restorations. The trial involves follow-up evaluations to monitor outcomes over time. During the study, dental restorations will be assessed at baseline, six months, and twelve months using FDI criteria to evaluate their clinical performance. Participants must maintain good oral hygiene and attend follow-up visits for up to two years. The study also monitors participants for any adverse effects and aims to gather detailed information on the durability and quality of each restoration type.

CONDITIONS

Brief Title

Comparison of Clinical Performance of Partial Restorations Fabricated With Three-Dimensional Printer and CAD-CAM

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with stable gums and appropriate oral hygiene without serious systemic diseases that prevent restoration
  • Male and female patients with hard tissue loss or two teeth needing restoration replacement
  • Individuals able to comply with treatment and willing to volunteer for follow-up for 2 years
Not Eligible

You will not qualify if you...

  • Patients with systemic conditions affecting the study process like diabetes or autoimmune diseases
  • Patients with excessive teeth grinding or other parafunctional habits
  • Pregnant or breastfeeding women
  • Patients with gum disease or severe bone loss
  • Patients with a history of allergic reactions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Single treatment session

Participants receive partial restorations fabricated either with a 3D printer or CAD-CAM technology.

1 treatment visit (in-person)

Follow-up

Duration - 12 months

Participants are followed to evaluate the clinical performance of their dental restorations over time.

3 visits at baseline, 6 months, and 12 months (in-person)

Trial Site Locations

Total: 1 location

1

Çukurova Üniversitesi Diş Hekimliği Fakültesi

Adana, Sarıçam, Turkey (Türkiye), 01250

Actively Recruiting

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Research Team

R

Research Assistant

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

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