Study Comparing Two Mechanical Thrombectomy Devices for Treating Acute Iliofemoral Deep Vein Thrombosis

What this Trial Is About

Researchers are evaluating two different devices for percutaneous mechanical thrombectomy PMT to treat patients with acute iliofemoral deep vein thrombosis DVT. This observational, prospective cohort study compares the ClotTriever System with aspiration thrombectomy including rheolytic thrombectomy to see if the ClotTriever System improves thrombus removal, reduces post-thrombotic syndrome PTS, and enhances the long-term results of endovascular treatment. Participants receive treatment using one of two types of mechanical thrombectomy devices. The ClotTriever System procedure is done through the ipsilateral popliteal vein or femoral vein, with access established under imaging guidance, followed by thrombectomy and evaluation of clot removal by venography. The aspiration thrombectomy group uses mechanical aspiration devices via similar vein access points, also assessing clot removal with venography. During the study, patients are monitored for PTS incidence at 24 months, with additional evaluations at 6, 12, and 24 months including PTS severity, clinical classification, vein patency, DVT recurrence, re-intervention rates, and quality of life. The study involves long-term follow-up to assess outcomes and safety. Participants sign informed consent and undergo endovascular treatment within 14 days of symptom onset.

Comparison Of Different Mechanical Thrombectomy Devices in Endovascular Treatment of Acute Iliofemoral Venous Thrombosis