Study to Check How Well Compression Ultrasound by Emergency Doctors Can Rule Out Proximal Deep Vein Thrombosis in Adults with Low Risk

What this Trial Is About

Researchers are evaluating the use of compression ultrasound performed by emergency physicians to exclude the diagnosis of proximal deep vein thrombosis DVT in patients with a low clinical probability of having DVT. The study aims to compare the accuracy of compression ultrasound to the D-Dimer assay, which is considered the gold standard, especially for patients with non-high clinical pretest probability. This investigation is sponsored by University Hospital, Strasbourg, France. Participants with clinical suspicion of DVT and a non-high probability score based on the modified Wells criteria will undergo compression ultrasound during their emergency department visit. The ultrasound will be performed as standard care to assess its predictive value in ruling out DVT. If the D-Dimer test is positive, a follow-up whole leg Doppler ultrasound will be done within 5 days. Throughout the study, researchers will monitor the negative predictive value of compression ultrasound to confirm the absence of DVT either during the emergency stay or within the 5-day follow-up for those with positive D-Dimer results. Participants will provide informed consent and be assessed for eligibility based on clinical criteria. The total study duration extends until February 2027, with continuous evaluation of ultrasound accuracy and safety in this setting.

Compression Ultrasonography in Non-high Probability of Deep Vein Thrombosis