Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
ID06639022

Comparison of the Postoperative Analgesic Efficacy of Serratus Posterior Superior Intercostal Plane Block and Erector Spinae Plane Block in Anterior Cervical Discectomy

Led by Ankara Etlik City Hospital · Updated on 2024-11-05

85

Participants Needed

1

Research Sites

5 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the pain relief effectiveness of two types of nerve blocks—the serratus posterior superior intercostal plane block and the erector spinae plane block—compared to no nerve block in patients undergoing anterior cervical discectomy. This surgery is done to relieve pressure on nerves caused by cervical disc disease using a microscopic approach from the front of the neck. The study aims to find which nerve block offers better pain control after surgery, potentially reducing opioid use and related risks. Participants are randomly assigned to one of three groups: one receiving the serratus posterior superior intercostal plane block with 30 ml of 0.25% bupivacaine under ultrasound guidance, another receiving the erector spinae plane block with the same dosing and method, and a control group undergoing surgery without a peripheral nerve block. All groups receive intravenous analgesics during surgery and multimodal pain management with paracetamol and dexketoprofen after surgery. During the study, patients will be monitored for pain scores on the day of surgery, and researchers will track opioid use during and after the operation. The study includes assessments of intraoperative remifentanil and tramadol consumption. The trial uses quadruple masking to reduce bias and will continue until November 2025, involving adults aged 18 to 80 years with specific health criteria.

CONDITIONS

Brief Title

Comparison of the Postoperative Analgesic Efficacy of SPSIPB and ESPB in Anterior Cervical Discectomy

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 to 80 years
  • American Society of Anesthesiologists (ASA) score I, II, or III
  • Body Mass Index (BMI) between 18 and 30 kg/m2
Not Eligible

You will not qualify if you...

  • Patients younger than 18 or older than 80 years
  • American Society of Anesthesiologists (ASA) score IV or higher
  • History of bleeding diathesis
  • Body Mass Index (BMI) below 18 or above 30 kg/m2

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surgery and Immediate Post-operative Care

Duration - 1 day

Participants undergo anterior cervical discectomy surgery with one of the nerve block procedures or no peripheral nerve block, followed by intraoperative and immediate postoperative analgesic treatment.

1 surgery day visit and immediate postoperative monitoring

Post-operative Follow-up

Duration - Operation day

Participants receive postoperative multimodal analgesia and pain is assessed on the operation day.

Visits during the operation day to monitor pain and analgesic use

Trial Site Locations

Total: 1 location

1

Ankara Etlik City Hospital

Altındağ, Ankara, Turkey (Türkiye), 06000

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Research Team

A

Atakan Sezgi

M

Musa Zengin

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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