Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
NCT06684275

Comparison of Pulsed and Thermal Radiofrequency for Trigeminal Neuralgia

Led by Zagazig University · Updated on 2024-12-31

60

Participants Needed

1

Research Sites

21 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to compare the effectiveness of Pulsed Radiofrequency (PRF) with Pulsed and Thermal Radiofrequency (PRF + TRF) in treating Trigeminal Neuralgia (TN) in adults. The main questions it aims to answer are: * Does PRF or PRF + TRF provide better pain relief for patients with trigeminal neuralgia? * What is the safety profile and complication rate of PRF versus PRF + TRF? Researchers will compare the effects of PRF and PRF + TRF to see if thermal lesioning in addition to pulsed RF provides superior long-term pain relief and reduces the need for analgesic medication. Participants will: * Undergo either PRF or PRF + TRF treatment targeting the trigeminal nerve. * Be assessed for pain relief, functional status, and adverse events over a 3-month follow-up period.

CONDITIONS

Official Title

Comparison of Pulsed and Thermal Radiofrequency for Trigeminal Neuralgia

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18-60 years
  • Diagnosis of classical trigeminal neuralgia as defined by international criteria
  • Unilateral, episodic facial pain lasting at least six months with a Numeric Rating Scale score greater than 6 despite medical treatment
  • Ability to provide informed consent
  • Willingness to follow study procedures and attend follow-up visits
Not Eligible

You will not qualify if you...

  • Secondary trigeminal neuralgia caused by tumors or multiple sclerosis
  • Previous surgery or radiofrequency treatment for trigeminal neuralgia
  • Pregnant or breastfeeding women
  • Allergies to anesthetics or agents used in the procedure
  • Significant psychiatric disorders affecting pain assessment or participation
  • Coagulopathy or use of anticoagulants that prevent the procedure

AI-Screening

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Trial Site Locations

Total: 1 location

1

Zagazig University, Faculty of Medicine

Zagazig, Sharqia Province, Egypt, 44519

Actively Recruiting

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Research Team

A

Ahmed A Bessar, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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