Actively Recruiting

Phase 1
Age: 18Years +
All Genders
NCT05451251

Deep Brain Stimulation for Refractory Trigeminal Neuralgia with a Pontine Lesion

Led by Université de Sherbrooke · Updated on 2024-12-12

6

Participants Needed

1

Research Sites

102 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this study is to assess the feasibility of deep brain stimulation for refractory trigeminal neuralgia due to a pontine lesion, as is usually seen in the context of multiple sclerosis. These patients usually have severe intractable facial pain and current medical and surgical options generally fail to achieve long lasting pain relief. Hoping to improve pain control in this population, the investigators of this trial propose a novel technique consisting of implanting a deep brain stimulation lead within the pontine lesion to modulate the generation of pain signals.

CONDITIONS

Official Title

Deep Brain Stimulation for Refractory Trigeminal Neuralgia with a Pontine Lesion

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults of at least 18 years old
  • Trigeminal neuralgia not responding to at least 3 drugs and 2 surgical interventions
  • MRI-confirmed pontine lesion in contact with the trigeminal nerve tract
Not Eligible

You will not qualify if you...

  • Absolute contraindication to MRI
  • Medical contraindication to the procedure

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Centre Hospitalier Universitaire de Sherbrooke (CHUS)

Sherbrooke, Quebec, Canada, J1H 5H3

Actively Recruiting

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Research Team

C

Christian Iorio-Morin, MD, PhD, FRCS(C)

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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