Actively Recruiting
Led by Afyonkarahisar Health Sciences University · Updated on 2026-01-13
78
Participants Needed
2
Research Sites
8 weeks
Total Duration
Carpal tunnel syndrome (CTS) is a common nerve compression condition causing numbness, tingling, muscle weakness, and hand atrophy. This research aims to compare the effects of rest splints and high-intensity laser therapy (HILT) combined with physical therapy programs on pain, function, nerve conduction, and grip strength for patients with CTS. The study is designed as a prospective randomized controlled trial to better understand these treatments' impacts on CTS symptoms and nerve function. Participants are divided into three groups. The first group receives a physical therapy program including wrist range of motion, strengthening, stretching, desensitization, tendon and nerve gliding exercises, and use of a resting splint for 6 weeks, five days a week (30 sessions total). The second group receives the same physical therapy plus high-intensity laser therapy over the carpal tunnel region daily for 6 weeks. The third group also follows the physical therapy program but receives a sham laser treatment mimicking the HILT without active laser emission to serve as a control. During the study, participants undergo assessments at baseline, after 6 weeks of treatment, and again at 12 weeks to measure pain using a Visual Analog Scale and other outcomes like function, sleep quality, neuropathic pain, nerve conduction studies, and grip strength. These evaluations include questionnaires, nerve tests, and strength measurements. The trial monitors participants' progress and treatment effects over time to determine the comparative benefits of rest splints and HILT when combined with physical therapy.
CONDITIONS
Comparison of Rest Splints vs High-Intensity Laser Therapy in Carpal Tunnel Syndrome
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 weeks
Participants receive a physical therapy program including wrist exercises. Depending on their group, they either use a resting splint daily for 6 weeks or receive high-intensity laser therapy or sham laser therapy five days a week for 6 weeks, alongside the physical therapy program.
30 treatment sessions (5 days a week)
Duration - 6 weeks
Participants are monitored after treatment to assess pain, function, nerve conduction, and grip strength.
Assessments at 6 weeks and 12 weeks post-treatment
Total: 2 locations
1
Afyonkarahisar Health Science University
Afyonkarahisar, Turkey (Türkiye), 0300
Not Yet Recruiting
2
Afyonkarahisar Health Sciences Unıversity
Afyonkarahisar, Turkey (Türkiye), 0300
Actively Recruiting
Ü
Ümit DÜNDAR, Profesor
R
Ramazan TUNCER, M.D
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
3
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